The aim of the research was to assess the applicability and efficacy of a practice that aligns the instruments and methods used within the mental health community to prevent and treat violence, with those employed by the human body to initiate and inhibit violence. Presenters assayed the applicability and efficacy of this practice through a feasibility study with mental health staff (n=750), and a pilot study with males in residential treatment with primary diagnoses associated with violence (n=10). Pilot data were subjected to Chi-square and ANOVA testing revealing statistically significant impact on violence-related outcome measures with 99% certainty. Capitalizing on homoeostatic processes honed over millennia invites the potential to join with biology to prevent violence at its origin and transform treatment. We are on the cusp of a revolution as interdisciplinary research and practitioner experience collide into a vanguard response to the age-old challenge of violence prevention and treatment.