The psychiatric High and Intensive Care (HIC) model is an innovative healthcare program in Belgium for inpatient treatment for severely disturbed psychiatric patients, focusing on intensive patient-centered integrated care with minimal coercive measures (van Mierlo et al., 2013). Our study is a multi-method approach of the implementation process of HIC across Belgium, as well as a longitudinal clinical-epidemiological approach to study patient profiles, changes in clinical outcomes during treatment, and after 6 and 12 months. Data are weighted to represent general patient profiles admitted in HIC units across Belgium. We present preliminary results on epidemiological profiles and clinical outcomes (aggression, suicide risk, psychiatric crisis, (perceived) coercion ) among the first 240 participants. We discuss implementation processes and generate hypotheses on factors related to decreases in clinical symptomatology and the use of coercive measures. We add to the knowledge on organizing services for severely disturbed psychiatric patients from innovative patient-centered perspectives.