Families and caregivers of children with intellectual disabilities have to deal with both the typical struggles that every household faces and those adjustments unique to these children including greater challenges in caregiving, more health problems, and feelings of isolation which results in poor quality of life (QOL). This study examines the relationship between a sense of coherence, dispositional optimism, and quality of life among parents of children with intellectual disability. Study used purposeful sampling with 30 parents who attend general services at NIEPID, Secunderabad, Telangana, India. The results indicated that a positive correlation was found between a sense of coherence and dispositional optimism, and coherence also correlated positively with parents of children with intellectual disabilities' psychological well-being. As a result, it suggested that a sense of coherence has an impact on quality of life and that a high sense of coherence correlates with a higher level of quality of life.